Immunofluorescence Method Improves Clinical Utility of Myeloma Cell Labeling Indices
نویسندگان
چکیده
منابع مشابه
Evaluation of clinical and histopathologic/direct immunofluorescence diagnosis in autoimmune vesiculobullous dermatitis: utility of direct immunofluorescence.
OBJECTIVE Autoimmune bullous diseases are heterogeneous diseases and the differentiation between the various bullous disease is important for treatment and prognosis. Direct immunofluorescence microscopy is still the gold standard in differentiating these diseases. Our aim was to determine the diagnostic accordance between clinical and histopathological/direct immunofluorescence diagnosis of pa...
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Immunofluorescence (IF) tests have redefined our understanding of many immune-mediated skin diseases, especially autoimmune blistering diseases (AIBDs). Nomenclature of certain AIBDs (for example, linear IgA diseases and IgA pemphigus) has been done based solely on the finding of tissue-bound immunoreactants as detected by IF tests. Direct and indirect are the two major types of IF tests; they ...
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Beta 2-microglobulin (beta 2M) has been proposed as a prognostic factor in multiple myeloma (MM), but beta 2M levels are reported to correlate with other prognostic indicators such as stage and creatinine level. This study addressed the independent prognostic values of these and other variables, including plasma cell labeling indices (LI), in patients with newly diagnosed MM. beta 2M levels wer...
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The patients examined in this study were the same cohort as in an earlier study of morphologic features2’ but with additional follow-up. Between March 1978 and February 1982, 100 patients were studied just prior to initial chemotherapy for MM; all were followed for at beast 3.5 years. Sufficient information was available on all patients to allow clinical staging, and bone marrow plasma cell LI ...
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The direct F.A. Method has been used for differentiation of virulent and avirulent lines of influenza viruses. A positive fluorescence was obtained indicating the level of virus in the tissues, sorbing with dried mouse powder helped to reduce non-specific staining. The virulent line showed the greatest number of fluorescent cells with the peak at 10 hours. the non-virulent lines showed a gra...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 1987
ISSN: 0025-6196
DOI: 10.1016/s0025-6196(12)65079-4